Nowadays, new compounds and wound dressings have received special attention in the treatment of many skin diseases due to the reduction of treatment time and cost. One of these compounds used is plant peptides, which are extracted from plants such as soybeans. Antimicrobial plant peptides are small, cationic and amphiphilic peptides that are secreted by fungi, plants, invertebrates and vertebrates and have antimicrobial activity against bacteria, fungi, viruses and other pathogens and act as non-specific host defense systems and the innate immune system. Another effective compound is Damask Rose essential oil, usually produced through steam distillation. Damask Rose has as many powerful anti-microbial and anti-aging compounds that are even against the very dangerous bacteria Escherichia and Staphylococcus aureus. Bacteria that resist even the strongest pharmaceutical antibiotics. This flower is rich in vitamin C and tannins, Vitamin C helps stimulate skin cells and collagen production, resulting in younger and rejuvenated skin. Vitamin C can also increase the brightness and color of the skin, close the pores and even clear acne and has a strengthening and antioxidant effect to prevent signs of aging. Damask Rose essential oil Keeps the skin moist. Damask Rose is a type of facial oil balancer to maintain a proper pH is absolutely essential for healthy skin. Our skin has a thin layer called an "acid mantle" that naturally fights infection and environmental factors. If the skin is too alkaline or too acidic, its ability to protect itself is reduced. Pollution, environmental toxins, and the sun's rays all play a role in disrupting the skin's pH balance. Fish collagen is resistant to physical and chemical damage. Additionally, the process of extracting this oil preserves the triple helix structure of collagen, thus keeping the polypeptide and amino acid intact. These proteins naturally supplement collagen and increase the therapeutic effects. There is another compound, The benefits of zinc oxide are, Help reduce inflammation caused by skin rashes, allergies, or skin irritations (including baby urine burns), Preventing sunburn and protecting the skin from the harmful rays of the sun (especially in photosensitive skin), Protecting the skin against all the harmful spectrum of ultraviolet rays (it can be said that zinc oxide is the only compound that filters all UV-A rays in addition to UV-B rays in broad-spectrum sunscreens.), Protection against skin cancer or neoplasia (cancer of the basal cells of the skin), Wound healing and prevention of bacterial infections, Helping to heal and fix burns and damaged and burnt tissue, Help to treat acne lesions, Retaining moisture in dry skin. Also, in this research, it is predicted that the use of the electrolysis method will cause proper homogenization of the additives on the surface of the matrix, which will increase the favorable effect of the polymer on the environment. In this research, in order to optimize (increase the efficiency with the least cost and time), it is tried that the polymeric phase of Polyvinyl alcohol has the highest amount available, which is expected to occupy 90% of the composition. According to the main structure of the sample created by the polymer, the variables of peptides, Damask Rose essential oil, Fish collagen oil and Zinc Oxide in several different ratios together in a fixed amount of polymer are investigated and evaluated. Considering that if the desired sample can have the highest efficiency in the highest amount of polymer and the lowest amount of actives, it can be easily stated that the desired sample has undergone optimization in addition to its antimicrobial efficiency. According to the mentioned cases and the introduction of the method and main materials of this research, in this research, it is tried to synthesize plant peptides/ Damask Rose essential oil/ Fish collagen/ Zinc oxide in the fixed polymer matrix of 90% total. SEM analysis will be used to investigate and obtain the structure and morphology of the synthesized sample. In order to investigate polymer resistance, the heating behavior of fibers during melting can be understood from tensile analysis and DSC analysis. According to the obtained results to investigate the antibacterial property to direct contact method against Escherichia coli bacteria, Aerobic mesophilic bacteria, Mold count, Pseudomonas aeruginosa enumeration count, Enumeration of staphylococcus aureus count and measurement of heavy metals (lead, arsenic, mercury, cadmium). Finally the obtained values ​​are compared with the reference value obtained from pure fibrous polymer under the same conditions. The results are reported in the form of effective data and are taken from the selected appropriate sample of the BET test.

Sahba Eslaminezhad has completed her MSc in 2020 from Islamic Azad University Shiraz and. She is founder of Pars Biotech Research & Development Company to produce health and treatment products with the latest technology and has received all the health permits from the Food and Drug Organization for this product. She has published several papers in reputed journals.