According to studies, sexual satisfaction is a key factor in a couple’s quality of life. The aim of this study was to evaluate the safety and efficacy of wormwood vaginal gel in improving sexual function and sexual satisfaction in women of reproductive age. This study was a randomized, triple-blinds, parallel-groups clinical trial performed on 76 women of reproductive age (18–45 years) who had sexual dysfunction and low sexual satisfaction. Wormwood gel or placebo was used for 4 weeks and 3 times a week for 4 weeks. The main data collection tools were the Female Sexual Function Index (FSFI)and Larson Sexual Satisfaction Questionnaire (LSSQ). Before the intervention, the Mean and Standard Deviation of the total score of sexual function and sexual satisfaction in the studied women were 17.70 ± 3.66 and 72.20 ± 6.56 in the intervention group and in the placebo group were 18.23 ± 3.84 and 73.26 ± 5.86, respectively. At the end of the intervention, the Mean and Standard Deviation of the total score of female sexual function and sexual satisfaction in the intervention group were 32.11 ± 2.03 and 96.91 ± 7.93 and in the placebo group were 21.07 ± 3.22 and 75.91 ± 8.87, respectively. Sexual function and satisfaction improved significantly in the wormwood gel compared to the control group(p < 0.0001).it seems that the wormwood vaginal gel can be used as a topical supplement to improve sexual function and sexual satisfaction in women of reproductive age who have sexual dysfunction and low sexual satisfaction.

Babazadeh is Assistant Professor in Reproductive Health, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Iran. He has published more than 50 papers in reputed journals and has been serving as a reviewer in several reputed journals.