Addressing the formidable challenge of combating COVID, healthcare systems are turning to nanotechnology. Nano-based formulations exhibit potential in enhancing antiviral medication delivery, treatment efficacy, and the creation of advanced vaccines with improved stability and controlled release. Nanotechnology contributes to rapid and accurate diagnosis, manufacturing potent disinfectants, delivering mRNA vaccines, and transporting antiviral drugs within the body, offering innovative solutions for managing the disease.