Health and social care systems currently undergo a transformation from phenomenological through evidence-based, person-centered, and personalized care towards personalized, preventive, predictive, participative precision medicine (5PM), supported by technology. 5PM considers individual health status, conditions, genetic and genomic dispositions in personal social, occupational, environmental and behavioral context, that way understanding the pathology of diseases and turning health and social care from reactive to proactive. Thereby, we have to enable communication and cooperation between all actors of the ecosystem, participating in different knowledge spaces, representing different disciplines, using different methodologies, perspectives, intentions, languages, etc. Therefore, the knowledge-based, multidisciplinary, highly complex and dynamic 5PM ecosystem must be consistently and formally represented. The outcome is a system-theoretical, architecture-centric, ontology-based, policy-driven approach for designing and managing intelligent and sustainable 5PM ecosystems.

Prof. Blobel studied Mathematics, Technical Cybernetics and Electronics, Theoretical Physics, Biocybernetics, Informatics, and Medicine at different universities in East Germany. He received the PhD degree in Physics, a habilitation in Medicine, and a habilitation in Medical Informatics. He was Head of the Physical Laboratory in Environmental Medicine at the Medical University Magdeburg and thereafter Head of the Medical Informatics Department and then Director of the Institute For Biometrics and Medical Informatics at the Medical Faculty of the Otto-von-Guericke University Magdeburg. In 2004, he became Founder and Head of the Health Telematics Project Group at Fraunhofer Society, Institute of Integrated Circuits (IIS), Erlangen, and thereafter Head of the German National eHealth Competence Center (eHCC) at the University of Regensburg. He is author of more than 450 scientific publications.