Russian Medical Academy of Continuous Professional Education, Russia
Aim. To assess cognitive functions in elderly patients with arterial
hypertension (AH) and concomitant chronic kidney disease (CKD).Methods. Three groups were formed according to medical records data: 1) patients
with AH (n=110, median age 76 [69,8;82,3] years), 2) patients with AH and CKD
stage 3a (n=110, median age 81[73,8;84,3] years), 3) patients with AH and CKD
stage 3b (n=110, median age 79,5 [72;85,3] years). Cognitive assessment
included MMSE, MoCA, DSST, VFT, ADAS-cog.
Findings. Patients with AH and CKD stage 3b had significantly lower MMSE
и MoCA scores (26 [24;28,3] and 23 [21;25] points) compared to group 1 (28
[25,8;29] and 24 [22;26] points; p=0.001 and p=0.034). Similarly, group 3 had
significantly lower DSST scores (19 [17;22]) compared to group 1 (21,5 [19;25];
p=0.045). VFT showed significantly lower verbal fluency in group 3 compared to
group one - 12 [11;13] and 11 [10;13] words, respectively (p=0.003). Group 3
had significantly higher ADAS-Cog score (15,5 [11;19]) compared to group 1 (11 [9;15];
p
Kantemir Dzamikhov – researcher, and physician at the Russian Medical Academy of Continuous Professional Education (Department of Therapy and multimorbid pathology named after academician M.S. Vovsi). Has publications in Russian and International journals in the scientific direction: of cognitive impairment in elderly patients. Member of the Russian Scientific Society of Internal Medicine (RSMSIM), European Federation of Internal Medicine Academy (EFIM Academy).