Addiction is intricately linked to brain disorders, disrupting neural circuits and function. Substance abuse alters the brain's reward system, leading to compulsive behaviors and diminished self-control. Neurotransmitter imbalances exacerbate the cycle, perpetuating addiction. Chronic substance use induces structural changes in the brain, particularly in areas governing decision-making and impulse control. Understanding addiction as a brain disorder highlights the need for comprehensive treatments addressing both physiological and psychological aspects. Combining pharmacological interventions with behavioral therapies is crucial for effectively managing addiction and promoting long-term recovery.