Objective; Suicidal behavior could be an important public health problem. The main objective of study was too lightness utilization of various antidepressants, additionally, their explicit types to forestall or reduce the risk of suicidal attempts. Materials and Methods; In total, 1348 patients of different ages were selected from different localities and alternative close regions and approved to participate in this study. Blood and urine samples obtained from everywhere the past few years from 2018 to 2021 once consent. Enzyme multiplying immunoassay technique (EMIT) is subject to the reference standard materials accustomed assess the precision and accuracy of the procedure. Gas chromatography-mass spectrum (GC – MS) used for confirmation of positive samples. Results; A statistically highly significant association was found relating to Para suicide in relevancy age and gender of patients (p = ≤ 0.003). A statistically significant distinction was found as regards Para suicide in association with type of drug overdose (p = 0.004). Findings from this review should be considered in light of potential limitations, such as the lack of comparative information concerning several antidepressants. Para suicide risks for selective serotonin reuptake inhibitor were significantly low than those of tricycles’ antidepressants,Conclusion; A substantial difference between different types of antidepressants was found, so in suicide prevention, risks and benefits of antidepressant should be taken into account when choosing treatment for depressive patients. Depressed patients should be under close psychiatric assessment in order to prevent such possible suicidal attempts

Dr. Raafat Mandour is an Associate Consultant (Professor) of toxicology Emergency Hospital Faculty of Medicine - Mansoura University at Egypt. Raafa Completed PhD hydro-geochemistry 2004 (between Science, Medicine and pharmacy colleges), Mansoura University and previously completed MSc in Hydro-geochemistry 2001 (Between Science and Medicine colleges) at the same institution Toxicology and forensic chemistry diploma (1996), faculty of medicine - Applied chemistry diploma (1993), faculty of science - Specializes in toxicology & forensic chemistry, water pollution, in addition to medical Analysis - Published papers over 14 local paper and 11 in international publications Spoken at 70 local conferences and workshops and 17 international meetings - Currently member of eight international scientific societies