After finishing medical school at Harvard, ophthalmology residency at Massachusetts Eye and Ear Infirmary, and a vitreo-retinal fellowship at the Medical College of Wisconsin, Dr. Sinclair spent 8 years as Assistant Professor of Ophthalmology and head of the vitreo-retinal service at the Hospital of the University of Pennsylvania in Philadelphia. He then migrated across town to Hahnemann University School of Medicine as Professor and of Ophthalmology to establish a new department as Chairman and then spent 6 years as vice-chairman of the Department. He left academia in 1993 and currently maintains a referral, private practice in vitreo-retinal diseases and surgery at in Media, Pennsylvania with affiliation at Riddle Memorial Hospital in the western and southwestern suburbs of Philadelphia. He remains as Adjunct Professor of Ophthalmology at Hahnemann, University teaching residents and students at Hahnemann and Temple Universities and at the Pennsylvania College of Optometry.