Modulating a small GTPase in the endothelium via targeted nanodelivery
Constantinos Mikelis University of Patras, GreeceExisting Vascular Endothelial Growth Factor (VEGF)-oriented anti-angiogenic approaches are known for their high potency. However, significant side e [....] Read More
Global Drug Development - Trends, Challenges & Opportunities
Gurpreet Singh IQVIA, UK• The entire process of developing a drug from preclinical research to marketing can take approximately 12 to 18 years and often costs well over [....] Read More
Understanding ABC transporters to navigate human diseases
Ruchika Bajaj University of California San Francisco, USA[....] Read More
Metal-based nanoclusters: Pharmacological and toxicity targets
Mirjana Colovic University of Belgrade, SerbiaMetal-based nanoparticles have been reported to possess promising properties as contrast-enhancing staining agents (CESAs) for computed tomography (CT [....] Read More
ABSTRACT: Sustained and controlled delivery of antimicrobial drugs has been largely studied using nanomaterials, like metal organic frameworks (MOFs [....] Read More
Bispecific CeY-B1 treatment for relapsed and refractory acute myeloid leukemia
Yanli Cui Zhejiang University, China
Based on years of research, a synthetic molecule CeY-B1 had designed and screened that effective against various tum [....] Read More
Currently, there is no cure for dementia and associated complications like cognitive impairment, and those available only offer symptomatic relief wi [....] Read More
Improved Bio-performance of DIA Transdermal Patch: In vivo and Ex vivo Proofs
Rajiv Kumar NIILM University, India
The study focuses developing drug-in-adhesive (DIA) transdermal patch of duloxetine HCl for improving drug delivery to systemic circulation. DIA pa [....] Read More
Dendrimers, which are a type of hyper-branched, three-dimensional, and nanostructural architecture polymers, exhibi [....] Read More
Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) is an isocratic method that is simple, specific, accurate, fast, and inexpensive. [....] Read More
Good distribution practices-warehouse storage and distribution practices as per WHO
Imran Ahmed Getz Pharma, PakistanDistribution is an important activity in the integrated supply-chain management of pharmaceutical products. Various people and entities are generally [....] Read More
Despite the availability and advancement of diagnostic and treatments with demonstrated benefits in minimizing card [....] Read More
Cancer is attributed to uncontrolled cell growth and is among the leading causes of death with no known effective treatment while complex tumor mic [....] Read More
A QSAR investigation was carried out on a diverse collection of thirty-eight isothiazole derivatives acting as NS5B inhibitors. The research methodo [....] Read More
Enhancing the solubility of pharmaceuticals with low water solubility has emerged as an effective approach for generating more efficient nanoparticl [....] Read More
Complex coacervation is one of the microencapsulation techniques by which encapsulated substances release profile improved. This study was conducted [....] Read More
Prevalence of use of Pain relievers in a Hospital in Bayelsa State, South-South of Nigeria
Owonaro A Peter Niger Delta University, NigeriaThe use of pain relievers to lower pain, inflammation, and temperature is a frequent practice all over the world. The study evaluated the most presc [....] Read More