Dr. Mikelis is an Associate Professor at the Department of Pharmacy at the University of Patras, in Greece. Till 2021 he was an Associate Professor at the School of Pharmacy of Texas Tech University Health Sciences Center, where he keeps an adjunct appointment. He was trained on vascular and cancer biology, with a focus on GPCR signaling at the National Institute of Dental and Craniofacial Research (NIDRC) at NIH, while his PhD at the University of Patras was focused on angiogenesis. His current research program is focused on investigating the role of small GTPases on endothelial physiology and cellular communication. By utilizing a repertoire of in vitro and in vivo models and innovative approaches his team is trying to elucidate their functional significance in human physiology and vascular-related pathological conditions.