Objective: The present study was carried out to evaluate the antitumor and antioxidant activities of the methanol extract of Cordia dichotoma (MECD) against EAC in Swiss albino mice. Materials and Methods: The present study evaluated the anticancer effect of the methanolic extract of Cordia dichotoma (MECD) bark against Ehrlich Ascites carcinoma (EAC) cells induced in albino mice and against human cancer cell lines (malondialdehyde-MB-231 andMCF-7cells).Results and Discussion: There was significant fall in the red blood cell count and hemoglobin (Hb) content, and a significant increase in white blood cell (WBC) count in the EAC control mice as compared to normal control mice. Treatment with MECD (500 mg/kg, b.w., p.o.) or 5-Fluorouracil (20 mg/kg b.w., i.p.)in EAC-cell bearing mice caused a significant (P < 0.01) increase in Hb levels while a significant (P < 0.01) decrease in WBC levels compared to EAC control rats. Further more, increase in the concentration of MECD dose-dependently increased the percent cytotoxicity and decreased the cell viability in both cell line types. The results with MECD were comparable to the tamoxifen. The maximum gain of body weight was observed in the EAC control group. In case of MECD and 5-Fluorouracil treated groups, the body weight was significantly (P < 0.01) reduced. The tumor volume and tumor weight were found to be significantly (P

Dr. Nazim Hussain Pharmacology, India graduated as M.Pharm in 2007. He then joined the Ph.D. as research scholar of Prof. B.B. Kakoti in the Department of Pharmaceutical Science, Dibrugarh University, India in 2012. He received his Ph.D. degree in 2019 at the same institution. After earning the Doctorate degree, he obtained the position of an Associate Professor at the North East Frontier Technical University, Aalo, Arunachal Pradesh, INDIA-791001 . He has published more than 10 research articles in SCI(E) journals.