Protein Based Vaccines
Protein Based Vaccines
Certain vaccines deviate from utilizing complete cells and instead rely on Tumour-Associated Antigen (TAA) proteins or their smaller fragments, known as TAA-derived peptides. These peptides encompass epitopes that MHC molecules on cell surfaces present, serving as targets for T cells to recognize tumour antigens. Peptide-based vaccines capitalize on computer algorithms' capability to scrutinize protein amino acid sequences, identifying potential peptide epitopes sourced from TAAs. This approach harnesses computational power to design vaccines with precision, enhancing their effectiveness in training the immune system to target tumour cells. By focusing on these specific antigenic fragments, peptide-based vaccines offer a tailored strategy in the realm of cancer immunotherapy.