Vector-borne diseases pose intricate challenges, rendering prevention and control remarkably difficult. Developing vaccines that target blood-feeding disease vectors, like ticks and mosquitoes, holds potential to shield against numerous illnesses triggered by vector-borne pathogens. These diseases often spread in residential areas, warranting a multifaceted approach for effective management. Employing vector control methods such as using insecticides on bed nets or through spraying, in conjunction with vaccines and medications, emerges as the most effective strategy. Tackling vector-borne diseases necessitates a comprehensive blend of tools to mitigate their impact, safeguarding public health in homes and communities